MIND OVER MATTER: "Depression is the inability to construct a future," is one of the most telling lines in Side Effects, a superbly twisty psychological thriller from Steven Soderbergh. Part psychosexual drama, part riveting character study, it takes on the world of pharmaceuticals and mental health in spinning the incredible story of Emily (Rooney Mara), a severely depressed young woman whose condition only seems to worsen when her husband, Martin (Channing Tatum) comes out of prison after four years for insider trading. After literally driving herself into a wall, Emily ends up in the care of a thoughtful psychologist (Jude Law), who puts her on a drug that appears to make matters worst. Catherine Zeta-Jones rounds out the main cast as a brainy shrink from Emily's past. In a nutshell, it's an absorbing, strongly acted film that brings into sharp focus the whole issue of prescribed treatment and their sometimes fatal "side effects." Rigorously engaging with the concepts of action and consequences and the dark side of human nature, Side Effects vividly shows that Soderbergh hasn't lost his deft touch when it comes to telling stories that pose difficult questions while challenging our notion of that thing we know as sanity. Tyrone's Verdict: A-
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